Marie was born on September 9, 1853, in Paris and died April 13, 1940. Pioneer neurologist whose discovery that growth disorders are caused by pituitary disease contributed to the modern science of endocrinology. A student of the famous French neurologist Jean Charcot at the Salpêtrière Hospital, Paris (1885), he published the first description of acromegaly (1886), a condition characterized by over-growth of bone tissue such as that of the nose, jaws, fingers, and toes, tracing the disease to a tumor of the pituitary gland, at the base of the brain.
He first described pulmonary osteoparthropathy (1890; inflammation of the bones and joints of the four limbs, often secondary to chronic conditions of the lungs and heart), hereditary cerebellar ataxia, also known as Marie’s ataxia (1893; a disease in young adults characterized by a failure of muscular coordination caused by an atrophy of the cerebellum); and (with Charcot) a type of progressive muscular atrophy known as the “Charcot-Marie type.” He served as professor of neurology at the University of Paris from 1907 to 1925. – The New Encyclopedia Britannica